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Silver Cross uses Optical Biopsies to See Cancer/Help Patients Avoid Unnecessary Surgery

Only 2nd hospital in Illinois to use new mini-microscope to diagnose/treat digestive diseases 

New Lenox, IL (May 15, 2014)—Using an advanced microscope, physicians at Silver Cross Hospital are now performing optical biopsies during endoscopic procedures to diagnose cancerous tissue in real time.  Silver Cross is only the second hospital (first non-teaching hospital) in Illinois to perform confocal endomicroscopy using new technology known as Cellvizio.   The result is a faster, more precise diagnosis and treatment of gastrointestinal cancer and other diseases. 

Photo Caption:  Dr. Kamran Ayub uses a mini flexible microscope allowing for an optical biopsy to diagnose and treat gastrointestinal cancer and other diseases. Silver Cross is only the second hospital in the state to use this advanced technology.

“Until now, if we found suspicious tissue during a diagnostic procedure, we had to take a sample and send it to the laboratory for analysis, which can take up to a week,” said Kamran Ayub, M.D., gastroenterologist and medical director of the Advanced Endoscopy Center at Silver Cross Hospital.  “With Cellvizio, we can locate the dangerous tissue during the initial endoscopic procedure and remove or treat it the same day.” 

Dr. Ayub and the team at Silver Cross Hospital in New Lenox are using this advanced technology to more accurately differentiate cancerous and pre-cancerous tissue during colonoscopies, upper endoscopies, and the standard pancreatic and bile duct cancer detection procedures.  They also use Cellvizio endomicroscopy to catch and treat gastrointestinal cancers and other diseases including those in the colon, bile duct, pancreas and esophagus.  In some cases, physicians have been able to perform minimally invasive treatments for conditions that traditionally required major surgical operations because of the microscopic view generated for an improved understanding of the tissue. 

World’s smallest microscope allows for immediate treatment

The new tool is a very small confocal laser microscope that sits at the end of a long, thin flexible tube.  The instrument is threaded through a traditional endoscope into the complex anatomy of the pancreas, bile ducts and other related tissues.  The microscope detects fluorescent light triggered by a laser.  A filter removes the laser light, allowing the fluorescent light to pass through a small aperture.  The light then hits a photo detector that converts the image to electronic signals.  The data then goes to a computer that displays the images on duals screens in one of the four Endoscopy suites in Silver Cross Hospital’s Procedural Care Unit.  One image from the microscope is worth 1,000 biopsies and can determine objects about half the diameter of a single hair. 

“I can immediately see cells up close and decide whether the next step of major surgery is necessary.  Often, I can treat the patient on the spot,” says Dr. Ayub. 

The technology is also used for monitoring patients with Barrett’s esophagus, a condition where there is an abnormal growth of intestinal-type cells in the lower esophagus.  

Cellvizio is has been approved by the Food & Drug Administration for use in gastrointestinal tract and lungs and has a proven safety record with no adverse events reported in thousands of cases worldwide. 

For a referral to a physician who performs Cellvizio endomicroscopy at Silver Cross Hospital, visit or call 1-888-660-HEAL (4325). 

About Silver Cross Hospital                             

Silver Cross Hospital is a not-for-profit health care provider serving Will County and southwest suburban communities since 1895. Silver Cross has been recognized as a Thomson Reuters 100 Top Hospitals National Award winner for seven consecutive years and as a Hospital of Choice by the American Alliance of Healthcare Providers. With over 3,000 employees, physicians and volunteers, Silver Cross operates a 289-bed acute care hospital and 5 satellite facilities providing outpatient services and physician offices. Silver Cross opened a state-of-the-art replacement hospital on February 26, 2012 at I-355 and Route 6 in New Lenox. In 2013, Silver Cross provided over $48 million in charity care and other community benefits. To learn more about Silver Cross Hospital or a referral to a physician on staff, visit or call 1-888-660-HEAL (4325). Physicians on Silver Cross Hospital’s Medical Staff have expertise in their areas of practice to meet the needs of patients seeking their care.  These physicians are independent practitioners on the Medical Staff and are not the agents or employees of Silver Cross Hospital. They treat patients based upon their independent medical judgment and they bill patients separately for their services.


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